Protein Interaction Antibody Pairs
ABclonal Technology Phospho-eIF4EBP1-T37/T46
This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation
ABclonal Technology Phospho-eIF4EBP1-S65
This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation
ABclonal Technology Phospho-eIF4EBP1-T37
This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation
ABclonal Technology NCK1 Rabbit mAb
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Bioss KD-Validated LDL receptor rela
LDL Receptor Related Protein 8 Primary Antibody Unconjugated Public Immunogen Range 900-963/963 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
ABclonal Technology Phospho-GSK3B-S9 Mouse mAb
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily It is a negative regulator of glucose homeostasis and is involved in energy metabolism inflammation ER-stress mitochondrial dysfunction and apoptotic pathways Defects in this gene have been associated with Parkinson disease and Alzheimer disease
ABclonal Technology Phospho-GSK3B-S9 Mouse mAb
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily It is a negative regulator of glucose homeostasis and is involved in energy metabolism inflammation ER-stress mitochondrial dysfunction and apoptotic pathways Defects in this gene have been associated with Parkinson disease and Alzheimer disease
ABclonal Technology p-PLC gamma 2 PLCG2-Y1217
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4 5-bisphosphate to 1D-myo-inositol 1 4 5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane Mutations in this gene have been found in autoinflammation antibody deficiency and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3
Sino Biological Recombinant Human CDK4 Protein (full length, GST Tag)
Recombinant full-length human CDK4 and CyclinD2 were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.
ABclonal Technology FasLG Rabbit pAb
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.